Nanoduct™ Neonatal Sweat Analysis System Early Cystic Fibrosis Diagnosis



GROUND BREAKING INNOVATION BASED ON PROVEN TECHNOLOGY

The Nanoduct Neonatal Sweat Analysis System combines and miniaturizes the proven collection and analysis technologies of Macroduct and Sweat-Chek to accommodate the tiny limbs of newborn infants, and provides reliable laboratory diagnosis of CF as soon as a newborn’s sweat glands are capable of producing sweat.

Innovative features of the Nanoduct System include the special electrode/sensor holders that are positioned on the patient’s limb before iontophoresis. The holders make electrode placement simple and secure. They also guarantee that the sensor collecting surface is perfectly registered with the stimulated skin area and attachment pressure is optimal when the sensor is attached.

Nanoduct incorporates the classic method of inducing sweat by pilocarpine iontophoresis. The pilocarpine is carried into the dermis of the patient from improved Pilogel® Iontophoretic Discs by a controlled DC electric current supplied by the Nanoduct System.

This is followed by continuous flow analysis of sweat electrolyte concentration using the unique conductivity sensor. Electrodes and the sensor are connected to the Nanoduct System via a single control cable.

The Nanoduct Neonatal Sweat Analysis System simplifies the sweat test and for the first time makes possible reliable laboratory diagnosis of CF in the first days of life.


Nanoduct
Nanoduct neonatal sweat system

CONTINUOUS-FLOW ANALYSIS OF ELECTROLYTE CONTENT

When the sensor is attached to the patient, the stimulated sweat emerging from the sweat glands is anaerobically directed into a microconductivity cell within the sensor. This provides a continuous display of the electrical conductivity in the freshly emerged sweat. Conductivity has been shown to be the equal of chloride in its ability to discriminate diagnostically between CF and non-CF subjects.
Nanoduct sensor

SEPARATE COLLECTION PHASE IS ELIMINATED

Continuous-flow analysis while the sensor is on the limb, eliminates potential handling errors, saves laboratory time, and ensures accuracy by providing virtually infinite replications of the analysis on freshly excreted sweat. A further benefit: any inadvertent contamination of the sensor collecting surface will be dissipated before the final reading is displayed.
NanoDuct Sweat Test

IMPROVED PILOGEL DISCS®
  1. Increased pilocarpine concentration
  2. Iontophoresis time reduced to only 2.5 minutes
  3. Buffered to prevent pH changes
 




Discovery Diagnostics
Canadian Customers
if you wish to speak to a Discovery Diagnostics sales representative or customer service, for information about Nanoduct™ Neonatal Sweat Analysis System Early Cystic Fibrosis Diagnosis, please call Toll Free within Canada: 1-888-883-9101.Outside Canada, click here for ordering information.